Adverse effects of testosterone replacement therapy: an update on the evidence and controversy

What Are the Side Effects of Testosterone Injections?

These side effects are typically dose-dependent and may vary from person to person. In conclusion, testosterone cypionate injections are a popular form of testosterone replacement therapy for men with low testosterone levels. While they have some potential side effects, such as polycythemia and skin-related issues, they also offer advantages in terms of consistent hormone release and dosage flexibility. It is crucial to weigh the potential risks and benefits and consult with a healthcare professional to determine the most suitable form of TRT for each individual’s needs. Another possible side effect of testosterone cypionate injections is an increase in red blood cell production. Testosterone can stimulate the bone marrow to produce more red blood cells, which can lead to an increase in the thickness or viscosity of the blood. This can increase the risk of blood clots or other cardiovascular complications.

Even though we administer hCG, our physicians still structure an effective PCT regimen to maximize therapeutic efficacy and ensure that testicular health and size are maintained. The PCT period usually consists of administering hCG for 5–20 consecutive days, depending on individual patient needs. The PCT period may be extended in patients who have suffered any form of testosterone injections related side effects. Additional supplementations typically accompany hCG in the PCT, according to the individual patient’s blood work and file details. It is worth noting that there are alternative forms of testosterone replacement therapy available, such as testosterone pellets implanted under the skin or buccal tablets that dissolve in the mouth.

You catch sight of some over-the-counter medication that promises to restore your sexual power. Cantharides If you see this ingredient on a bottle, it’s another … Their patients are educated throughout the treatment process regarding lifestyle modifications such as diet, exercise, vitamins, and getting proper sleep to ensure proper hormone production is well-supported. Please note that all of these potential side effects are rare and are readily reversible by contacting the prescribing doctor at once to notify of these changes and receive a lowering of the dosage to administer. If testosterone levels get too high, a person may have more serious symptoms, such as signs of liver toxicity. Evidence suggests that many people taking testosterone for hypogonadism have never had their testosterone levels checked or, if they have had their levels checked, do not meet the threshold for low testosterone.

That means that difference between testosterone and estrogen therapy by itself won’t always help erectile dysfunction. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Other prescription and over-the-counter medicines, vitamins, and herbal products may also react with testosterone. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

However, there was a higher incidence of pulmonary embolism, acute kidney injury, and atrial fibrillation among men who received testosterone replacement. This isn’t a big deal for most people, he says, and its more common to see it if you’re taking a non-daily treatment like an injection, where you’re getting a higher dose of T in one sitting. Sperm production may or may not go back to normal after stopping treatment, says Dr. Kaminetsky. A 2017 study in Fertility & Sterility found that increasing age and longer length of T-therapy were linked to lower chances of normal sperm recovery. Muscles respond to testosterone, and starting T-therapy can increase muscle mass, says Dr. Morgentaler. That’s because testosterone activates the androgen receptors in muscle tissue to stimulate growth.

We do not guarantee the accuracy, completeness, or usefulness of the information provided. We are not responsible for any errors or omissions, and any reliance on the information is at your own risk. Testosterone supplements increases the RBC count of the bloodstream. If it goes very high, the blood becomes too thick and there are possible chances of blood clotting in veins. If any of these effects occur please tell your doctor at Innovative Men’s Clinic promptly. However, if you are giving this medication to yourself at home, we will review proper use in the clinic and if you have any questions or concerns, it is important to contact us as soon as possible.

When it comes to fertility, there’s a hormone called Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH), these hormone signals become disrupted with testosterone shots. Because of this FSH downregulation, it may become impossible to conceive or produce some real man gravy during intercourse. Another common side effect is the genetic conversion of excess testosterone to DHT (dihydrotestosterone) which can predispose some to lose the hair on top of their heads. Miniaturizing hair follicles can primarily be genetic naturally without TRT shots, however, increased conversion of Testosterone to DHT can be an underlying issue that is not dealt with through the use of TRT shots. Men who may have a lot of body fat tissue may be more susceptible to converting the injected testosterone to estrogen. This can cause male breast enlargement, puffy nipples, and extreme discomfort in the localized area. When it comes to masculinity, bone mass, fat distribution, muscle mass, and drive are all very important for men’s health.

Anxiety about obtaining or maintaining an erection during sexual intercourse may lead some men to have less control over ejaculation. The good news is that ED can be treated quickly, at any age with the Innovative approach. This medication can decrease sperm production, an effect that may lower male fertility.

Likewise, testosterone has been shown to improve hemodynamic parameters via a reduction in peripheral vascular resistance and increased coronary blood flow through vasodilation, thereby improving functional and symptomatic status. To date, growth hormone and testosterone therapy have shown some positive benefits, albeit with some concerns over adverse effects. However, large randomized controlled trials are still needed to assess the long-term safety and efficacy.